Capsaicin and nociception in the rat and mouse

  title={Capsaicin and nociception in the rat and mouse},
  author={Rainer Gamse},
  journal={Naunyn-Schmiedeberg's Archives of Pharmacology},
Newborn or adult rats and mice were treated with capsaicin. The effect of systemic or intrathecal treatment on thermonociception, chemonociception, content and release of immunoreactive substance P (I-SP) was investigated. Treatment of two day old rats caused a small, but life-long elevation of the hot plate or tail withdrawal latency. Treatment of adult rats led to a large increase in the reaction time on the hot plate for 4–10 days but the tail withdrawal latency was only slightly elevated… CONTINUE READING
52 Citations
52 References
Similar Papers


Publications citing this paper.
Showing 1-10 of 52 extracted citations


Publications referenced by this paper.
Showing 1-10 of 52 references

Behavioural and electrophysiological studies related to nociception in capsaicintreated rats

  • TE Salt, RG Hill, PMB Cahusac, R Morris
  • 1982
3 Excerpts

Effect of neonatal administration of capsaicin in several nociceptive systems of the rat

  • F Cervero, HA McRitchie
  • Bonica JJ, Liebeskind JC, Albe-Fessard DG (eds…
  • 1982
1 Excerpt

Similar Papers

Loading similar papers…