Capsaicin and its analogue resiniferatoxin inhibit gastric acid secretion in pylorus-ligated rats.

@article{Salam1995CapsaicinAI,
  title={Capsaicin and its analogue resiniferatoxin inhibit gastric acid secretion in pylorus-ligated rats.},
  author={Omar M. E. Abdel Salam and J{\'a}nos Szolcs{\'a}nyi and Gyula M{\'o}zsik},
  journal={Pharmacological research},
  year={1995},
  volume={31 6},
  pages={341-5}
}
The effect of capsaicin and its analogue resiniferatoxin on gastric acid secretion was studied in conscious pylorus-ligated rats. Capsaicin administered intragastrically (i.g.) in very low concentrations inhibited gastric acid secretion (GAS) in a dose-dependent manner. The effect was most pronounced in the first hour. Resiniferatoxin administered in low concentrations like capsaicin produced a similar dose-dependent inhibition of GAS. The antisecretory action of both compounds was not present… CONTINUE READING

From This Paper

Topics from this paper.

Similar Papers

Loading similar papers…