Capsaicin, a structural analog of tyrosine, inhibits the aminoacylation of tRNA(Tyr).


Because of its structural homology to capsaicin, the amino acid tyrosine appeared as a potential analog of the toxin and, consequently, could be a tool that could be used to clarify the mechanism of action of capsaicin. The in vitro experimental system was used to determine whether tyrosine and capsaicin effectively compete for tyrosyl-tRNA synthetase… (More)


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