Capillary zone electrophoresis of basic analytes in methanol as non-aqueous solvent mobility and ionisation constant.


The electrophoretically relevant properties of monoacidic 21 bases (including common drugs) containing aliphatic or aromatic amino groups were determined in methanol as solvent. These properties are the actual mobilities (that of the fully ionised weak bases), and their pKa values. Actual mobilities were measured in acidic methanolic solutions containing… (More)