Capillary volume fraction is the principal determinant of villous membrane thickness in the normal human placenta at term.


The thickness of the villous membrane is known to be an important factor in determining the morphometric diffusing capacity of the placenta at term. As yet it is not certain how areas of the villous membrane specialised for gaseous exchange, the vasculo-syncytial membranes, differentiate. One mechanism suggested is that they arise through obtrusion of the… (More)


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