Capillary permeability is increased in normo- and microalbuminuric type 1 diabetic patients: amelioration by ACE-inhibition.

@article{Oomen1999CapillaryPI,
  title={Capillary permeability is increased in normo- and microalbuminuric type 1 diabetic patients: amelioration by ACE-inhibition.},
  author={Peter H N Oomen and Jos Jager and Klaas Hoogenberg and Robin P F Dullaart and W. D. Reitsma and Andries J. Smit},
  journal={European journal of clinical investigation},
  year={1999},
  volume={29 12},
  pages={1035-40}
}
BACKGROUND Capillary leakage of sodium-fluorescein (NaF) in the skin reflects capillary permeability and may be a marker of diabetes-associated microcirculatory abnormalities. DESIGN We evaluated transcapillary skin NaF leakage by fluorescence videodensitometry in 10 normoalbuminuric, 10 microalbuminuric Type 1 diabetic men (diabetes duration > 10 years) and 10 healthy subjects. The microalbuminuric patients were restudied after 6 weeks treatment with the ACE-inhibitor enalapril, 10 mg once… CONTINUE READING
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