Capecitabine Therapy of Central Nervous System Metastases from Breast Cancer

@article{Ekenel2007CapecitabineTO,
  title={Capecitabine Therapy of Central Nervous System Metastases from Breast Cancer},
  author={Meltem Ekenel and A Hormigo and S ott M Peak and Lisa M DeAngelis and Lauren Eileen Abrey},
  journal={Journal of Neuro-Oncology},
  year={2007},
  volume={85},
  pages={223-227}
}
Central nervous system (CNS) metastases from breast cancer carry a poor prognosis. Systemic chemotherapy is often ineffective due to the impermeability of the blood-brain barrier (BBB) and inherent chemoresistance of CNS metastases. There are limited data supporting the use of capecitabine in this setting. Medical records of seven patients with brain metastases from breast cancer who received capecitabine treatment at Memorial Sloan-Kettering Cancer Center from 1994–2006 were reviewed… CONTINUE READING