Capacity of human monocytes to phagocytose approved iron oxide MR contrast agents in vitro

@article{Metz2004CapacityOH,
  title={Capacity of human monocytes to phagocytose approved iron oxide MR contrast agents in vitro},
  author={Stephan Metz and Gabriel Bonaterra and Martina Rudelius and Marcus Settles and Ernst J. Rummeny and Heike E. Daldrup-Link},
  journal={European Radiology},
  year={2004},
  volume={14},
  pages={1851-1858}
}
To evaluate the capacity of human monocytes to phagocytose various approved iron oxide based magnetic resonance (MR) contrast agents and to optimize in vitro labeling of these cells. Human monocytes were incubated with two superparamagnetic iron oxide particles (SPIO) as well as two ultrasmall SPIO (USPIO) at varying iron oxide concentrations and incubation times. Iron uptake in monocytes was proven by histology, quantified by atomic emission absorption spectrometry and depicted with T2… CONTINUE READING
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