Capacitative calcium entry


A long-standing mystery in the cell biology of calcium channel regulation is the nature of the signal linking intracellular calcium stores to plasma membrane capacitative calcium entry channels. An RNAi-based screen of selected Drosophila genes has revealed that a calcium-binding protein, stromal interaction molecule (STIM), plays an essential role in the activation of these channels and may be the long sought sensor of calcium store content.

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@article{Putney2005CapacitativeCE, title={Capacitative calcium entry}, author={James W. Putney}, journal={The Journal of Cell Biology}, year={2005}, volume={169}, pages={381 - 382} }