CapZ and actin capping dynamics increase in myocytes after a bout of exercise and abates in hours after stimulation ends.

@article{Lin2013CapZAA,
  title={CapZ and actin capping dynamics increase in myocytes after a bout of exercise and abates in hours after stimulation ends.},
  author={Ying-Hsi Lin and Jieli Li and Erik R. Swanson and Brenda Russell},
  journal={Journal of applied physiology},
  year={2013},
  volume={114 11},
  pages={1603-9}
}
The time course of the response and recovery after acute activity seen in exercise is not well understood. The goal of this work is to address how proteins of the thin filament (actin and its capping protein CapZ) are changed by 1 h of mechanical stimulation and return to baseline over time. Neonatal rat ventricular myocytes in culture were subjected to cyclic 10% strain at 1 Hz for 1 h to mimic increased mechanical loading during exercise. CapZ and actin dynamics were analyzed by fluorescence… CONTINUE READING
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