Canonical and alternative MAPK signaling.

  title={Canonical and alternative MAPK signaling.},
  author={Genaro Pimienta and Jaime Pascual},
  journal={Cell cycle},
  volume={6 21},
The archetype of MAPK cascade activation is somewhat challenged by the most recent discovery of unexpected phosphorylation patterns, alternative activation mechanisms and sub-cellular localization, in various members of this protein kinase family. In particular, activation by autophosphorylation pathways has now been described for the three best understood… CONTINUE READING