Canonical Genetic Signatures of the Adult Human Brain

@inproceedings{Hawrylycz2015CanonicalGS,
  title={Canonical Genetic Signatures of the Adult Human Brain},
  author={Michael J Hawrylycz and Jeremy A. Miller and Vilas Menon and David Feng and Tim Dolbeare and Angela L. Guillozet-Bongaarts and Anil G. Jegga and Bruce J. Aronow and Chang-Kyu Lee and Amy Bernard and Matthew F. Glasser and Donna L. Dierker and J{\"o}rg Menche and Aaron Szafer and Forrest Collman and Pascal Grange and Kenneth A. Berman and Stefan Mihalas and Zizhen Yao and Lance J. Stewart and Albert-L{\'a}szl{\'o} Barab{\'a}si and Jay Schulkin and John W.P. Phillips and Lydia L. Ng and Chinh Dang and David R. Haynor and Allan R. Jones and David C Van Essen and Christof Koch and Ed S Lein},
  booktitle={Nature Neuroscience},
  year={2015}
}
The structure and function of the human brain are highly stereotyped, implying a conserved molecular program responsible for its development, cellular structure and function. We applied a correlation-based metric called differential stability to assess reproducibility of gene expression patterning across 132 structures in six individual brains, revealing mesoscale genetic organization. The genes with the highest differential stability are highly biologically relevant, with enrichment for brain… CONTINUE READING
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References

Publications referenced by this paper.
SHOWING 1-10 OF 47 REFERENCES

BRAIN NETWORKS. Correlated gene expression supports synchronous activity in brain

J Richiardi
  • 2015

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