Cannabis use and risk of psychotic or affective mental health outcomes: a systematic review
@article{Moore2007CannabisUA, title={Cannabis use and risk of psychotic or affective mental health outcomes: a systematic review}, author={Theresa Hm Moore and Stanley Zammit and Anne Lingford-Hughes and Thomas R. E. Barnes and Peter B. Jones and Margaret Burke and Glyn Lewis}, journal={The Lancet}, year={2007}, volume={370}, pages={319-328} }
2,029 Citations
Effects of cannabis use on outcomes of psychotic disorders: systematic review
- Medicine, PsychologyBritish Journal of Psychiatry
- 2008
Confidence that most associations reported were specifically due to cannabis is low, and it remains important to establish whether cannabis is harmful, what outcomes are particularly susceptible, and how such effects are mediated.
Cannabis use and mania symptoms: a systematic review and meta-analysis.
- Medicine, PsychologyJournal of affective disorders
- 2015
Does giving up substance use work for patients with psychosis? A systematic meta-analysis
- Psychology, MedicineThe Australian and New Zealand journal of psychiatry
- 2012
It is suggested that substance use contributes to both the symptoms and the burden of disability experienced by patients with psychosis.
Cannabis Use and the Risk for Psychosis and Affective Disorders
- Psychology, MedicineJournal of dual diagnosis
- 2019
The evidence that heavy use of high-THC/low-CBD types of cannabis increases the risk of psychosis is sufficiently strong to merit public health education and the possibility that CBD may be therapeutically useful.
An overview of systematic reviews on cannabis and psychosis: discussing apparently conflicting results.
- Medicine, PsychologyDrug and alcohol review
- 2010
It is concluded that there is insufficient knowledge to determine the level of risk associated with cannabis use in relation to psychotic symptoms and that more information is needed on both the risks of cannabis use and the benefits of preventive interventions to support evidence-based approaches.
Meta-analysis of the Association Between the Level of Cannabis Use and Risk of Psychosis.
- Psychology, MedicineSchizophrenia bulletin
- 2016
Current evidence shows that high levels of cannabis use increase the risk of psychotic outcomes and confirms a dose-response relationship between the level of use and the risk for psychosis, and sufficient evidence to justify harm reduction prevention programs.
[Cannabis and mood].
- Psychology, MedicineRevista brasileira de psiquiatria
- 2010
The relationship between cannabis use and mood changes are observed both in the epidemiological research and in the clinical settings.
Brief interventions for cannabis use in emerging adults: A systematic review, meta-analysis, and evidence map.
- Medicine, PsychologyDrug and alcohol dependence
- 2019
Cannabis and Psychosis: A Review of the Risk Factors Involved
- Psychology, Medicine
- 2020
A significant inverse relationship exists between cannabidiol (CBD) and psychosis: cannabodiol is associated with less psychotic symptoms and manifests antipsychotic properties.
Risk-thresholds for the association between frequency of cannabis use and the development of psychosis: a systematic review and meta-analysis.
- Medicine, PsychologyPsychological medicine
- 2022
Individuals using cannabis frequently are at increased risk of psychosis, with no significant risk associated with less frequent use, which should be refined through further work.
References
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The available evidence supports the hypothesis that cannabis is an independent risk factor for psychosis and the development of psychotic symptoms, particularly in vulnerable populations, and is likely to have beneficial effects on psychiatric morbidity.
Cannabis use and psychosis: a longitudinal population-based study.
- Psychology, MedicineAmerican journal of epidemiology
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Results confirm previous suggestions that cannabis use increases the risk of both the incidence of psychosis in psychosis-free persons and a poor prognosis for those with an established vulnerability to psychotic disorder.
P.3.a.031 Prospective cohort study of cannabis use, predisposition for psychosis, and psychotic symptoms in young people
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Cannabis use moderately increases the risk of psychotic symptoms in young people but has a much stronger effect in those with evidence of predisposition for psychosis.
Causal association between cannabis and psychosis: examination of the evidence
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Cases of psychotic disorder could be prevented by discouraging cannabis use among vulnerable youths and research is needed to understand the mechanisms by which cannabis causes psychosis.
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In participants with no baseline depressive symptoms, those with a diagnosis of cannabis abuse at baseline were four times more likely than those with no cannabis abuse diagnosis to have depressive symptoms at the follow-up assessment, after adjusting for age, gender, antisocial symptoms, and other baseline covariates.
Cannabis use in adolescence and risk for adult psychosis: longitudinal prospective study
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This is the first prospective longitudinal study of adolescent cannabis use as a risk factor for adult schizophreniform disorder, taking into account childhood psychotic symptoms, and the Dunedin multidisciplinary health and development study has a 96% follow up rate at age 26.
Cannabis dependence and psychotic symptoms in young people
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The results show that the development of cannabis dependence is associated with increased rates of psychotic symptoms in young people even when pre-existing symptoms and other background factors are taken into account.
Psychological and social sequelae of cannabis and other illicit drug use by young people: a systematic review of longitudinal, general population studies
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Tests of causal linkages between cannabis use and psychotic symptoms.
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The present study suggests that the association between cannabis use and psychotic symptoms is unlikely to be due to confounding factors; and the direction of causality is from cannabis use to psychotic symptoms.
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Heavy cannabis use and depression are associated and evidence from longitudinal studies suggests that heavy cannabis use may increase depressive symptoms among some users, but it is still too early, however, to rule out the hypothesis that the association is due to common social, family and contextual factors that increase risks of both heavy cannabis Use and depression.