Cannabis use and risk of psychotic or affective mental health outcomes: a systematic review

@article{Moore2007CannabisUA,
  title={Cannabis use and risk of psychotic or affective mental health outcomes: a systematic review},
  author={Theresa Hm Moore and Stanley Zammit and Anne Lingford-Hughes and Thomas R. E. Barnes and Peter B. Jones and Margaret Burke and Glyn Lewis},
  journal={The Lancet},
  year={2007},
  volume={370},
  pages={319-328}
}
BACKGROUND Whether cannabis can cause psychotic or affective symptoms that persist beyond transient intoxication is unclear. We systematically reviewed the evidence pertaining to cannabis use and occurrence of psychotic or affective mental health outcomes. METHODS We searched Medline, Embase, CINAHL, PsycINFO, ISI Web of Knowledge, ISI Proceedings, ZETOC, BIOSIS, LILACS, and MEDCARIB from their inception to September, 2006, searched reference lists of studies selected for inclusion, and… Expand
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Current evidence shows that high levels of cannabis use increase the risk of psychotic outcomes and confirms a dose-response relationship between the level of use and the risk for psychosis, and sufficient evidence to justify harm reduction prevention programs. Expand
[Cannabis and mood].
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The relationship between cannabis use and mood changes are observed both in the epidemiological research and in the clinical settings. Expand
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It is indicated that BIs targeting non-treatment seeking emerging adults result in significant reductions in symptoms of cannabis use disorder and an increased likelihood of cannabis abstinence, however evidence is of low quality. Expand
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TLDR
A systematic review of meta-analyses and systematic reviews to evaluate the impact of cannabis use on the onset and course of psychoses found that cannabis use is associated with a dose-dependent risk of developing psychotic illness, and cannabis users have an earlier onset of psychotic illness compared to non-users. Expand
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