• Corpus ID: 12547408

Cannabis use and risk of psychotic or aff ective mental health outcomes: a systematic review

@inproceedings{Moore2007CannabisUA,
  title={Cannabis use and risk of psychotic or aff ective mental health outcomes: a systematic review},
  author={Theresa Hm Moore and Stanley Zammit and Anne Lingford-Hughes and Thomas R. E. Barnes and Peter B. Jones and Margaret Burke and Glyn Lewis},
  year={2007}
}
Methods We searched Medline, Embase, CINAHL, PsycINFO, ISI Web of Knowledge, ISI Proceedings, ZETOC, BIOSIS, LILACS, and MEDCARIB from their inception to September, 2006, searched reference lists of studies selected for inclusion, and contacted experts. Studies were included if longitudinal and population based. 35 studies from 4804 references were included. Data extraction and quality assessment were done independently and in duplicate. 
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TLDR
The available evidence supports the hypothesis that cannabis is an independent risk factor for psychosis and the development of psychotic symptoms, particularly in vulnerable populations, and is likely to have beneficial effects on psychiatric morbidity.
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TLDR
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TLDR
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Cases of psychotic disorder could be prevented by discouraging cannabis use among vulnerable youths and research is needed to understand the mechanisms by which cannabis causes psychosis.
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TLDR
The results show that the development of cannabis dependence is associated with increased rates of psychotic symptoms in young people even when pre-existing symptoms and other background factors are taken into account.
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TLDR
The present study suggests that the association between cannabis use and psychotic symptoms is unlikely to be due to confounding factors; and the direction of causality is from cannabis use to psychotic symptoms.
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