Cannabis Withdrawal, Posttreatment Abstinence, and Days to First Cannabis Use Among Emerging Adults in Substance Use Treatment

@article{Davis2016CannabisWP,
  title={Cannabis Withdrawal, Posttreatment Abstinence, and Days to First Cannabis Use Among Emerging Adults in Substance Use Treatment},
  author={Jordan P. Davis and Douglas Cary Smith and Jason W. Morphew and Xinrong Lei and Saijun Zhang},
  journal={Journal of Drug Issues},
  year={2016},
  volume={46},
  pages={64 - 83}
}
Very little prospective research investigates how cannabis withdrawal is associated with treatment outcomes, and this work has not used the Diagnostic and Statistical Manual of Mental Disorders (5th ed.; DSM-5) thresholds for cannabis withdrawal. The sample included 110 emerging adults entering outpatient substance use treatment who were heavy cannabis users with no other drug use and limited alcohol use. We used survival analyses to predict days to first use of cannabis and logistic regression… 

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References

SHOWING 1-10 OF 99 REFERENCES
Withdrawal symptoms do not predict relapse among subjects treated for cannabis dependence.
TLDR
This is the first follow-up study on the association between cannabis withdrawal symptoms and risk of relapse to cannabis use and offers further validation of a cannabis withdrawal syndrome.
Quantifying the Clinical Significance of Cannabis Withdrawal
TLDR
Cannabis withdrawal is clinically significant because it is associated with functional impairment to normal daily activities, as well as relapse to cannabis use.
Cannabis withdrawal symptoms in non-treatment-seeking adult cannabis smokers.
Cannabis withdrawal in adolescent treatment seekers.
Cannabis withdrawal among non-treatment-seeking adult cannabis users.
TLDR
Study findings provide evidence for the clinical significance of a cannabis withdrawal syndrome, based on the high prevalence and co-occurrence of multiple symptoms that follow a consistent time course and that prompt action by the subjects to obtain relief, including serving as negative reinforcement for cannabis use.
Cannabis withdrawal in chronic, frequent cannabis smokers during sustained abstinence within a closed residential environment.
TLDR
Abstinence symptoms were generally more intense in the initial phase, implying importance of early intervention in cannabis quit attempts and sleep disturbance persisting for an extended period suggests that hypnotic medications could be beneficial in treating cannabis dependence.
Diagnostic criteria for cannabis withdrawal syndrome.
...
...