Cannabinoids modulate hippocampal memory and plasticity.

  title={Cannabinoids modulate hippocampal memory and plasticity.},
  author={Hila Abush and Irit Akirav},
  volume={20 10},
Considerable evidence demonstrates that cannabinoid agonists impair whereas cannabinoid antagonists improve memory and plasticity. However, recent studies suggest that the effects of cannabinoids on learning do not necessarily follow these simple patterns, particularly when emotional memory processes are involved. We investigated the involvement of the cannabinoid system in hippocampal learning and plasticity using the fear-related inhibitory avoidance (IA) and the non-fear-related spatial… CONTINUE READING