Cannabinoids in treatment-resistant epilepsy: A review

@article{OConnell2017CannabinoidsIT,
  title={Cannabinoids in treatment-resistant epilepsy: A review},
  author={B. K. O'Connell and D. Gloss and O. Devinsky},
  journal={Epilepsy & Behavior},
  year={2017},
  volume={70},
  pages={341-348}
}
Treatment-resistant epilepsy (TRE) affects 30% of epilepsy patients and is associated with severe morbidity and increased mortality. Cannabis-based therapies have been used to treat epilepsy for millennia, but only in the last few years have we begun to collect data from adequately powered placebo-controlled, randomized trials (RCTs) with cannabidiol (CBD), a cannabis derivative. Previously, information was limited to case reports, small series, and surveys reporting on the use of CBD and… Expand
125 Citations
Cannabidiol Treatment for Refractory Epilepsies in Pediatrics
  • 1
Cannabinoids in the Treatment of Epilepsy: Hard Evidence at Last?
  • E. Perucca
  • Medicine
  • Journal of epilepsy research
  • 2017
  • 104
  • PDF
The potential role of cannabinoids in epilepsy treatment
  • 18
Cannabidiol Therapy for Refractory Epilepsy and Seizure Disorders.
  • 1
Efficacy of cannabinoids in pharmacoresistant epilepsy: A narrative review of the literature
  • 1
  • Highly Influenced
  • PDF
Emerging Use of Epidiolex (Cannabidiol) in Epilepsy.
  • 2
...
1
2
3
4
5
...

References

SHOWING 1-10 OF 83 REFERENCES
Cannabidiol in patients with treatment-resistant epilepsy: an open-label interventional trial
  • 486
  • PDF
Whole Cannabis Extract of High Concentration Cannabidiol May Calm Seizures in Highly Refractory Pediatric Epilepsies
  • 9
  • Highly Influential
  • PDF
Report of a parent survey of cannabidiol-enriched cannabis use in pediatric treatment-resistant epilepsy
  • 278
  • PDF
Cannabidiol: Pharmacology and potential therapeutic role in epilepsy and other neuropsychiatric disorders
  • 534
  • PDF
The pharmacologic treatment of Dravet syndrome
  • 115
  • PDF
Cannabinoids for epilepsy.
  • 190
  • PDF
Parental reporting of response to oral cannabis extracts for treatment of refractory epilepsy
  • 155
Cannabidiol as a Potential Treatment for Febrile Infection-Related Epilepsy Syndrome (FIRES) in the Acute and Chronic Phases
  • 86
  • PDF
Cannabidiol as a new treatment for drug‐resistant epilepsy in tuberous sclerosis complex
  • 114
  • Highly Influential
...
1
2
3
4
5
...