Cannabinoids activate mesolimbic dopamine neurons by an action on cannabinoid CB1 receptors.

@article{Gessa1998CannabinoidsAM,
  title={Cannabinoids activate mesolimbic dopamine neurons by an action on cannabinoid CB1 receptors.},
  author={Gian Luigi Gessa and Miriam Melis and Anna Muntoni and Marco Diana},
  journal={European journal of pharmacology},
  year={1998},
  volume={341 1},
  pages={39-44}
}
The present study was designed to determine if cannabinoids share with other drugs of abuse the ability to stimulate mesolimbic dopaminergic neurons and if this effect is mediated by cannabinoid receptors. To this end, the effects of the prototypical cannabinoid, delta9 tetrahydrocannabinol ¿(-)-trans-(6aR,10aR)-6a,7,8,10a-tetrahydro-6,6,9-trimethyl- 3-pentyl-6H-dibenzo[b,d]pyran-1-ol¿, and the two highly potent synthetic cannabinoids, ¿(R)-(+)-[2,3-dihydro-5-methyl-3-[(4-morpholinyl)-methyl… CONTINUE READING
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To this end , the effects of the prototypical cannabinoid , delta9 tetrahydrocannabinol ¿
To this end , the effects of the prototypical cannabinoid , delta9 tetrahydrocannabinol ¿
To this end , the effects of the prototypical cannabinoid , delta9 tetrahydrocannabinol ¿
To this end , the effects of the prototypical cannabinoid , delta9 tetrahydrocannabinol ¿
The present study was designed to determine if cannabinoids share with other drugs of abuse the ability to stimulate mesolimbic dopaminergic neurons and if this effect is mediated by cannabinoid receptors .
The stimulant response to cannabinoids was suppressed by the specific cannabinoid receptor antagonist ¿
These findings support the contention that cannabinoids regulate mesolimbic dopamine transmission and may help to explain the addictive properties of marijuana .
To this end , the effects of the prototypical cannabinoid , delta9 tetrahydrocannabinol ¿
To this end , the effects of the prototypical cannabinoid , delta9 tetrahydrocannabinol ¿
To this end , the effects of the prototypical cannabinoid , delta9 tetrahydrocannabinol ¿
To this end , the effects of the prototypical cannabinoid , delta9 tetrahydrocannabinol ¿
To this end , the effects of the prototypical cannabinoid , delta9 tetrahydrocannabinol ¿
To this end , the effects of the prototypical cannabinoid , delta9 tetrahydrocannabinol ¿
The present study was designed to determine if cannabinoids share with other drugs of abuse the ability to stimulate mesolimbic dopaminergic neurons and if this effect is mediated by cannabinoid receptors .
The stimulant response to cannabinoids was suppressed by the specific cannabinoid receptor antagonist ¿
These findings support the contention that cannabinoids regulate mesolimbic dopamine transmission and may help to explain the addictive properties of marijuana .
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