Cannabinoid therapies in the management of sleep disorders: A systematic review of preclinical and clinical studies.

@article{Suraev2020CannabinoidTI,
  title={Cannabinoid therapies in the management of sleep disorders: A systematic review of preclinical and clinical studies.},
  author={Anastasia Suraev and Nathaniel S Marshall and Ryan Vandrey and Danielle McCartney and Melissa J Benson and Iain S. McGregor and Ronald R. Grunstein and Camilla M Hoyos},
  journal={Sleep medicine reviews},
  year={2020},
  volume={53},
  pages={
          101339
        }
}
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45 Citations
Background Citations
12
Methods Citations
2

45 Citations

Effects of Cannabinoids on Sleep and their Therapeutic Potential for Sleep Disorders.

  • M. KaulP. ZeeA. Sahni
  • Medicine, Psychology
    Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics
  • 2021
The results indicate a potential therapeutic role for cannabinoids in the management of some sleep disorders, but there remains a substantial need for rigorous large multi-center studies to assess the dose, efficacy, and safety of the various types of cannabinoids on sleep disorders.

Cannabinoid treatments for anxiety: A systematic review and consideration of the impact of sleep disturbance

Medical Cannabis and Cannabinoids for Impaired Sleep: A Systematic Review and Meta-Analysis of Randomized Clinical Trials.

Medical cannabis and cannabinoids may improve impaired sleep among people living with chronic pain, but the magnitude of benefit is likely small.

The Effectiveness and Safety of Cannabidiol in Non-seizure-related Indications: A Systematic Review of Published Randomized Clinical Trials

While cannabidiol was generally safe and well tolerated even in high doses among the included studies, clearer dosing guidelines and increased regulation of cannabis-derived compounds are also needed.

Endocannabinoid System as Therapeutic Target of PTSD: A Systematic Review

Evidence about the efficacy and safety of medicinal cannabidiol (CBD), Δ9-tetrahydrocannabinol (Δ9-THC), and nabilone in PTSD treatment is summarized.

Is There a Place for Medicinal Cannabis in Treating Patients with Sleep Disorders? What We Know so Far

This narrative review summarizes the highest quality clinical evidence currently available in relation to the use of medicinal cannabis for the treatment of sleep disorders including insomnia, obstructive sleep apnea, restless legs syndrome, rapid eye movement sleep behavior disorder, nightmare disorder and narcolepsy.

Potential Role of Cannabidiol on Sports Recovery: A Narrative Review

Evidence suggesting that CBD has the potential to be used as a part of the strategies to recover from fatigue and muscle damage related to physical and cognitive exertion in sports is examined.

The Effects of Cannabinoids on Sleep

It is shown that cannabis products have minimal to no effects on sleep disorders and may have deleterious effects in some individuals and further research examining the differential impact of the various types of cannabinoids that are currently available on each of these sleep disorders is required.

Treating insomnia symptoms with medicinal cannabis: a randomized, crossover trial of the efficacy of a cannabinoid medicine compared with placebo

Two weeks of nightly sublingual administration of a cannabinoid extract (ZTL-101) is well tolerated and improves insomnia symptoms and sleep quality in individuals with chronic insomnia symptoms.

Cannabidiol (CBD) in Rheumatic Diseases (Musculoskeletal Pain)

CBD has potential for relief of symptoms of pain, sleep, and mood disturbance in rheumatology patients, but sound clinical evidence is lacking and the healthcare community must urgently accrue sound evidence for effect.

References

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