Cannabinoid receptors as novel targets for the treatment of melanoma.

  title={Cannabinoid receptors as novel targets for the treatment of melanoma.},
  author={Cristina Bl{\'a}zquez and Arkaitz Carracedo and Luc{\'i}a Barrado and Pedro J Real and Jos{\'e} Luis Fern{\'a}ndez-Luna and Guillermo Velasco and Marcos Malumbres and Manuel Alejandro P{\'e}rez Guzm{\'a}n},
  journal={FASEB journal : official publication of the Federation of American Societies for Experimental Biology},
  volume={20 14},
Melanoma causes the greatest number of skin cancer-related deaths worldwide. Despite intensive research, prevention and early detection are the only effective measures against melanoma, so new therapeutic strategies are necessary for the management of this devastating disease. Here, we evaluated the efficacy of cannabinoid receptor agonists, a new family of potential antitumoral compounds, at skin melanoma. Human melanomas and melanoma cell lines express CB1 and CB2 cannabinoid receptors… CONTINUE READING
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