Cannabinoid receptors are absent in insects

  title={Cannabinoid receptors are absent in insects},
  author={J. Mcpartland and V. Di Marzo and L. De Petrocellis and A. Mercer and M. Glass},
  journal={Journal of Comparative Neurology},
  • J. Mcpartland, V. Di Marzo, +2 authors M. Glass
  • Published 2001
  • Biology, Medicine
  • Journal of Comparative Neurology
  • The endocannabinoid system exerts an important neuromodulatory role in mammals. Knockout mice lacking cannabinoid (CB) receptors exhibit significant morbidity. The endocannabinoid system also appears to be phylogenetically ancient—it occurs in mammals, birds, amphibians, fish, sea urchins, leeches, mussels, and even the most primitive animal with a nerve network, the Hydra. The presence of CB receptors, however, has not been examined in terrestrial invertebrates (or any member of the Ecdysozoa… CONTINUE READING
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