Cannabinoid receptors and pain

@article{Pertwee2001CannabinoidRA,
  title={Cannabinoid receptors and pain},
  author={R. Pertwee},
  journal={Progress in Neurobiology},
  year={2001},
  volume={63},
  pages={569-611}
}
  • R. Pertwee
  • Published 2001
  • Medicine, Biology
  • Progress in Neurobiology
  • Mammalian tissues contain at least two types of cannabinoid receptor, CB(1) and CB(2), both coupled to G proteins. CB(1) receptors are expressed mainly by neurones of the central and peripheral nervous system whereas CB(2) receptors occur centrally and peripherally in certain non-neuronal tissues, particularly in immune cells. The existence of endogenous ligands for cannabinoid receptors has also been demonstrated. The discovery of this 'endocannabinoid system' has prompted the development of a… CONTINUE READING

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    References

    Publications referenced by this paper.
    SHOWING 1-10 OF 235 REFERENCES
    Pharmacology of cannabinoid receptor ligands.
    487
    Pharmacology of cannabinoid CB1 and CB2 receptors.
    1306