Cannabinoid receptor type 2 activation yields delayed tolerance to focal cerebral ischemia.

@article{Zhu2011CannabinoidRT,
  title={Cannabinoid receptor type 2 activation yields delayed tolerance to focal cerebral ischemia.},
  author={Miaozhang Zhu and Zhenghua Zhu and Yu Zhao and Lihong Hou and Qiang Wang and Lize Xiong and Xiaoling Zhu and Ji Zeng Jia and Shaoyang Chen},
  journal={Current neurovascular research},
  year={2011},
  volume={8 2},
  pages={
          145-52
        }
}
We demonstrated in our previous research that pretreatment with electroacupuncture (EA) induces rapid (2h after EA) and delayed (24h after EA) tolerance to focal cerebral ischemia. We further elucidate the endocannabinoid and cannabinoid receptor type 1(CB1) involvment in the rapid ischemic tolerance induced by EA pretreatment. The present study aimed at investigating the involvement of the cannabinoid receptor type 2 (CB2) in the neuroprotection conferred by EA pretreatment. Focal cerebral… CONTINUE READING
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