Cannabinoid receptor 1 in the vagus nerve is dispensable for body weight homeostasis but required for normal gastrointestinal motility.

@article{Vianna2012CannabinoidR1,
  title={Cannabinoid receptor 1 in the vagus nerve is dispensable for body weight homeostasis but required for normal gastrointestinal motility.},
  author={Claudia R. Vianna and Jos{\'e} Luis Donato and Jari Rossi and M. A. Scott and Kyriakos D Economides and Lauren Gautron and Stephanie Pierpont and Carol F Elias and Joel K Elmquist},
  journal={The Journal of neuroscience : the official journal of the Society for Neuroscience},
  year={2012},
  volume={32 30},
  pages={10331-7}
}
The cannabinoid receptor 1 (CB(1)R) is required for body weight homeostasis and normal gastrointestinal motility. However, the specific cell types expressing CB(1)R that regulate these physiological functions are unknown. CB(1)R is widely expressed, including in neurons of the parasympathetic branches of the autonomic nervous system. The vagus nerve has been implicated in the regulation of several aspects of metabolism and energy balance (e.g., food intake and glucose balance), and… CONTINUE READING