Cannabinoid effects on plasma corticosterone and uptake of 3H-corticosterone by mouse brain.

@article{Johnson1978CannabinoidEO,
  title={Cannabinoid effects on plasma corticosterone and uptake of 3H-corticosterone by mouse brain.},
  author={Kenneth M. Johnson and William L. Dewey and Karla S. Ritter and J. S. Beckner},
  journal={European journal of pharmacology},
  year={1978},
  volume={47 3},
  pages={
          303-10
        }
}
View on PubMed
doi.org
23 Citations
Background Citations
7
Methods Citations
1
Results Citations
1

23 Citations

Function of Cannabinoid Receptors in the Neuroendocrine Regulation of Hormone Secretion

Although cannabinoid receptors appear to play a major role in the ability of cannabinoids to influence hormone release, much remains to be learned concerning their function in the neuroendocrine regulation of hormone secretion.

Interaction of ambient temperature with the effects of Δ9 on brain catecholamine synthesis and plasma corticosterone levels

The data indicate that the effects of THC on brain catecholamines are not a result of drug induced hypothermia and may be a results of a direct action on neurons.

Cortical 3α-hydroxy-5α-pregnan-20-one levels after acute administration of Δ9-tetrahydrocannabinol, cocaine and morphine

To determine if other abused drugs elicit alterations in brain neurosteroid levels, Δ9-tetrahydrocannabinol, cocaine and morphine were administered to male rats and elevated cortical allopregnanolone levels to pharmacologically active levels.

Behavioral and biochemical effects of chronic Δ9-tetrahydrocannabinol in rats

None of the currently investigated biochemical changes correlated with the marked behavioral and physiological changes after initial THC administration to which tolerance develops, suggesting the syndrome of compulsive motor routines after prolonged THC treatment might be mediated by elevated brain 5-HT activity.

Differential effects of cannabinoid exposure and stress on plasma prolactin, growth hormone and corticosterone levels in male mice.

Monoacylglycerol lipase inhibition-induced changes in plasma corticosterone levels, anxiety and locomotor activity in male CD1 mice

Endocrine and other responses to acute administration of cannabinoid compounds to non-stressed male calves.

Corticotrophin and corticosterone secretion following Δ1-tetrahydrocannabinol, in intact and in hypothalamic deafferentated male rats

It is demonstrated that acute treatment with THC stimulates the secretion of ACTH as well as of CS; and that extrahypothalamic sites and/or neural pathways mediate this effect.

Endocannabinoid signaling in hypothalamic–pituitary–adrenocortical axis recovery following stress: Effects of indirect agonists and comparison of male and female mice

The role of corticotropin-releasing factor in drug addiction.

The goal of this article is to summarize available data examining the physiological significance of brain corticotropin-releasing factor (CRF) systems in mediating the behavioral and physiological…

References

SHOWING 1-10 OF 25 REFERENCES

Delta 9-THC: selective impairment of corticosterone uptake by limbic structures of the rat.

Uptake of corticosterone by rat brain and its concentration by certain limbic structures.

Corticosterone elevation mediated centrally by Δ1-tetrahydrocannabinol in rats

The anticonvulsant activity of cannabidiol and cannabinol.

Comparative Pharmacology of Δ9-Tetrahydrocannabinol and its Metabolite, 11-OH-Δ9-Tetrahydrocannabinol

It is suggested that in man, A9-THC, the active constituent in marihuana, is converted to 11-OHY9-Tetrahydrocannabinol, which is in part responsible for the psychologic effects.

Effects of ACTH and corticosteroids on single neurons in the hypothalamus.

Retention of corticosterone by cell nuclei from brain regions of adrenalectomized rats.

Evidence of Inhibitive Role of Hippocampus in Neural Regulation of ACTH Release.∗

  • K. KniggeM. Hays
  • Biology, Medicine
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine
  • 1963
The results support the opinion that hippocampus contributes an inhibitory component to the neural mechanisms regulating ACTH release to lesioned, unresponsive animals.

Distribution of Marihuana in Monkey Brain and Concomitant Behavioural Effects

Dose level and route of administration of Δ9-tetrahydrocannabinol (Δ9-THC), the principal psychoactive constituent of Cannabis sativa, to subjective and objective physiological, behavioural and mentational effects are attempted.

Intravenous Injection in Man of Δ9-Tetrahydrocannabinol and 11-OH-Δ9-Tetrahydrocannabinol

Intravenous infusion of this preparation to humans indicates that both tetrahydrocannabinols are equally potent in producing the typical marihuana-like pschological and physiological effects.