Cannabinoid administration increases 5HT1A receptor binding and mRNA expression in the hippocampus of adult but not adolescent rats

@article{Zavitsanou2010CannabinoidAI,
  title={Cannabinoid administration increases 5HT1A receptor binding and mRNA expression in the hippocampus of adult but not adolescent rats},
  author={K. Zavitsanou and Hong Wang and V. Dalton and V. Nguyen},
  journal={Neuroscience},
  year={2010},
  volume={169},
  pages={315-324}
}
  • K. Zavitsanou, Hong Wang, +1 author V. Nguyen
  • Published 2010
  • Biology, Medicine
  • Neuroscience
  • The endocannabinoid and serotonin systems share a high level of overlap in terms of the physiological processes that they regulate, however, little is known about their functional interactions particularly during adolescence, a vulnerable period for both the development of psychosis and for initiation to substance use. In the present study, the effects of cannabinoid treatment on serotonin 5HT1A receptor density and mRNA expression were investigated in two age groups: Adolescent (postnatal day… CONTINUE READING
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