Cannabinoid Receptors: Where They are and What They do

@article{Mackie2008CannabinoidRW,
  title={Cannabinoid Receptors: Where They are and What They do},
  author={K. Mackie},
  journal={Journal of Neuroendocrinology},
  year={2008},
  volume={20}
}
  • K. Mackie
  • Published 2008
  • Chemistry, Medicine
  • Journal of Neuroendocrinology
The endocannabinoid system consists of the endogenous cannabinoids (endocannabinoids), cannabinoid receptors and the enzymes that synthesise and degrade endocannabinoids. Many of the effects of cannabinoids and endocannabinoids are mediated by two G protein‐coupled receptors (GPCRs), CB1 and CB2, although additional receptors may be involved. CB1 receptors are present in very high levels in several brain regions and in lower amounts in a more widespread fashion. These receptors mediate many of… Expand
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