Cannabinoid CB1 receptors mediate the effects of dipyrone.

  title={Cannabinoid CB1 receptors mediate the effects of dipyrone.},
  author={Fernanda Crunfli and Fabiana Cardoso Vilela and Alexandre Giusti-Paiva},
  journal={Clinical and experimental pharmacology & physiology},
  volume={42 3},
Dipyrone is a non-steroidal anti-inflammatory drug used primarily as an analgesic and antipyretic. Some hypothesize that dipyrone activity can modulate other pathways, including endocannabinoid signalling. Thus, the aim of the present study was to evaluate the possible role of endocannabinoids in mediating dipyrone activity. This study is based on the… CONTINUE READING