Cannabinoid CB1 receptor-mediated inhibition of the neurogenic vasopressor response in the pithed rat

@article{Malinowska1997CannabinoidCR,
  title={Cannabinoid CB1 receptor-mediated inhibition of the neurogenic vasopressor response in the pithed rat},
  author={Barbara Malinowska and Grzegorz Godlewski and Bernard Bucher and Eberhard Schlicker},
  journal={Naunyn-Schmiedeberg's Archives of Pharmacology},
  year={1997},
  volume={356},
  pages={197-202}
}
The effects of two cannabinoid receptor agonists, R(+)-[2,3-dihydro-5-methyl-3-[(morpholinyl)methyl]-pyrrolo[1, 2, 3-de]-1,4-benzoxazin-yl]-(1-naphthalenyl)methanone (WIN 55,212-2) and (-)-cis-3-[2-hydroxy-4-(1,1-dimethylheptyl)phenyl]-trans-4-(3-hydroxypropyl)cyclohexanol (CP-55,940), were studied on (i) the vasopressor response elicited in pithed rats by electrical stimulation of the sympathetic outflow and (ii) the release of 3H-noradrenaline and the vasoconstriction elicited in isolated rat… CONTINUE READING
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