Cannabinoid CB1 receptor antagonists as potential pharmacotherapies for drug abuse disorders.

@article{Beardsley2009CannabinoidCR,
  title={Cannabinoid CB1 receptor antagonists as potential pharmacotherapies for drug abuse disorders.},
  author={Patrick M. Beardsley and Brian F. Thomas and Lance R. McMahon},
  journal={International review of psychiatry},
  year={2009},
  volume={21 2},
  pages={134-42}
}
Since the discovery of the cannabinoid CB1 receptor (CB1R) in 1988, and subsequently of the CB2 receptor (CB2R) in 1993, there has been an exponential growth of research investigating the functions of the endocannabinoid system. The roles of CB1Rs have been of particular interest to psychiatry because of their selective presence within the CNS and because of their association with brain-reward circuits involving mesocorticolimbic dopamine systems. One potential role that has become of… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 14 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 78 references

Similar Papers

Loading similar papers…