Cannabinoid–Opioid Interaction in Chronic Pain

@article{Abrams2011CannabinoidOpioidII,
  title={Cannabinoid–Opioid Interaction in Chronic Pain},
  author={D. Abrams and P. Couey and S. Shade and M. E. Kelly and N. Benowitz},
  journal={Clinical Pharmacology & Therapeutics},
  year={2011},
  volume={90}
}
Cannabinoids and opioids share several pharmacologic properties and may act synergistically. The potential pharmacokinetics and the safety of the combination in humans are unknown. We therefore undertook a study to answer these questions. Twenty–one individuals with chronic pain, on a regimen of twice–daily doses of sustained–release morphine or oxycodone were enrolled in the study and admitted for a 5–day inpatient stay. Participants were asked to inhale vaporized cannabis in the evening of… Expand
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Interventional Clinical Trial
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ConditionsInflammatory Bowel Diseases
InterventionDrug
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