Cannabimovone, a Cannabinoid with a Rearranged Terpenoid Skeleton from Hemp

  title={Cannabimovone, a Cannabinoid with a Rearranged Terpenoid Skeleton from Hemp},
  author={Orazio Taglialatela‐Scafati and Alberto Pagani and Fernando Scala and Luciano Petrocellis and Vincenzo Di Marzo and Gianpaolo Grassi and Giovanni Appendino},
  journal={European Journal of Organic Chemistry},
An investigation of the polar fractions from a nonpsychotropic variety of hemp (Cannabis sativa L.) afforded cannabimovone (6), a polar cannabinoid with a rearranged 2(3→4) abeo-terpenoid skeleton, biogenetically originating from the intramolecular aldolization of a 2',3'-seco-menthanyl precursor. The structure of cannabimovone was elucidated by spectroscopic analysis, whereas attempts to mimic its biogenetic derivation from cannabidiol (2) gave only anhydrocannabimovone (12), the… 
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