Cannabidiol inhibits the hyperlocomotion induced by psychotomimetic drugs in mice.

@article{Moreira2005CannabidiolIT,
  title={Cannabidiol inhibits the hyperlocomotion induced by psychotomimetic drugs in mice.},
  author={Fabr{\'i}cio A Moreira and Francisco Silveira Guimar{\~a}es},
  journal={European journal of pharmacology},
  year={2005},
  volume={512 2-3},
  pages={
          199-205
        }
}
  • Fabrício A Moreira, Francisco Silveira Guimarães
  • Published 2005
  • Chemistry, Medicine
  • European journal of pharmacology
  • Cannabidiol is a non-psychotomimetic compound from Cannabis sativa. It is proposed as a possible antipsychotic drug, since it can prevent some psychotomimetic-like effects of Delta9-tetrahydrocannabinol or apomorphine. Therefore, the aim of this work was to test the hypothesis that cannabidiol would inhibit the hyperlocomotion induced by two psychotomimetic drugs, D-amphetamine or ketamine. Male Swiss mice received i.p. injections of haloperidol (0.15-0.6 mg/kg), clozapine (1.25-5 mg/kg) or… CONTINUE READING

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