Cannabidiol exhibits anxiolytic but not antipsychotic property evaluated in the social interaction test

@article{Almeida2013CannabidiolEA,
  title={Cannabidiol exhibits anxiolytic but not antipsychotic property evaluated in the social interaction test},
  author={V. Almeida and R. Levin and F. F. Peres and S. T. Niigaki and M. Calzavara and A. W. Zuardi and J. Hallak and J. Crippa and V. Ab{\'i}lio},
  journal={Progress in Neuro-Psychopharmacology and Biological Psychiatry},
  year={2013},
  volume={41},
  pages={30-35}
}
  • V. Almeida, R. Levin, +6 authors V. Abílio
  • Published 2013
  • Psychology, Medicine
  • Progress in Neuro-Psychopharmacology and Biological Psychiatry
  • Cannabidiol (CBD), a non-psychotomimetic compound of the Cannabis sativa, has been reported to have central therapeutic actions, such as antipsychotic and anxiolytic effects. We have recently reported that Spontaneously Hypertensive Rats (SHRs) present a deficit in social interaction that is ameliorated by atypical antipsychotics. In addition, SHRs present a hyperlocomotion that is reverted by typical and atypical antipsychotics, suggesting that this strain could be useful to study negative… CONTINUE READING
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    References

    SHOWING 1-10 OF 82 REFERENCES
    Antipsychotic profile of cannabidiol and rimonabant in an animal model of emotional context processing in schizophrenia.
    • 34
    Effects of antipsychotics and amphetamine on social behaviors in spontaneously hypertensive rats
    • 42
    Effect of cannabidiol in a MK-801-rodent model of aspects of Schizophrenia
    • 63
    Cannabidiol, a Cannabis sativa constituent, as an antipsychotic drug.
    • 343
    • PDF
    A critical review of the antipsychotic effects of cannabidiol: 30 years of a translational investigation.
    • 143
    • PDF
    Neural basis of anxiolytic effects of cannabidiol (CBD) in generalized social anxiety disorder: a preliminary report
    • 254
    • PDF
    Anxiolytic-like effect of cannabidiol in the rat Vogel conflict test
    • 146
    Effects of cannabidiol in animal models predictive of antipsychotic activity
    • 150
    Distinct effects of d‐amphetamine and phencyclidine on the social behaviour of rats
    • 145
    Effects of cannabidiol and diazepam on behavioral and cardiovascular responses induced by contextual conditioned fear in rats
    • 117
    • Highly Influential