Cannabidiol exhibits anxiolytic but not antipsychotic property evaluated in the social interaction test

  title={Cannabidiol exhibits anxiolytic but not antipsychotic property evaluated in the social interaction test},
  author={V. Almeida and R. Levin and F. F. Peres and S. T. Niigaki and M. Calzavara and A. W. Zuardi and J. Hallak and J. Crippa and V. Ab{\'i}lio},
  journal={Progress in Neuro-Psychopharmacology and Biological Psychiatry},
  • V. Almeida, R. Levin, +6 authors V. Abílio
  • Published 2013
  • Psychology, Medicine
  • Progress in Neuro-Psychopharmacology and Biological Psychiatry
  • Cannabidiol (CBD), a non-psychotomimetic compound of the Cannabis sativa, has been reported to have central therapeutic actions, such as antipsychotic and anxiolytic effects. We have recently reported that Spontaneously Hypertensive Rats (SHRs) present a deficit in social interaction that is ameliorated by atypical antipsychotics. In addition, SHRs present a hyperlocomotion that is reverted by typical and atypical antipsychotics, suggesting that this strain could be useful to study negative… CONTINUE READING
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