Cannabidiol enhances the inhibitory effects of delta9-tetrahydrocannabinol on human glioblastoma cell proliferation and survival.

@article{Marcu2010CannabidiolET,
  title={Cannabidiol enhances the inhibitory effects of delta9-tetrahydrocannabinol on human glioblastoma cell proliferation and survival.},
  author={Jahan P. Marcu and Rigel T. Christian and Darryl Lau and Anne J. Zielinski and Maxx P. Horowitz and Jasmine Lee and Arash Pakdel and Juanita Allison and Chandani Limbad and D Helen Moore and Garret L. Yount and Pierre-Yves Desprez and Sean D. McAllister},
  journal={Molecular cancer therapeutics},
  year={2010},
  volume={9 1},
  pages={180-9}
}
The cannabinoid 1 (CB(1)) and cannabinoid 2 (CB(2)) receptor agonist Delta(9)-tetrahydrocannabinol (THC) has been shown to be a broad-range inhibitor of cancer in culture and in vivo, and is currently being used in a clinical trial for the treatment of glioblastoma. It has been suggested that other plant-derived cannabinoids, which do not interact efficiently with CB(1) and CB(2) receptors, can modulate the actions of Delta(9)-THC. There are conflicting reports, however, as to what extent other… CONTINUE READING
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