Cannabidiol as a potential treatment for psychosis

@article{Schubart2014CannabidiolAA,
  title={Cannabidiol as a potential treatment for psychosis},
  author={Christian D. Schubart and I. Sommer and Paolo Fusar-Poli and Lot D. de Witte and R. S. Kahn and Marco P. M. Boks},
  journal={European Neuropsychopharmacology},
  year={2014},
  volume={24},
  pages={51-64}
}
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Available evidence suggests that CBD may attenuate both psychotic-like symptoms induced by THC in healthy volunteers and positive symptoms in individuals with schizophrenia, and preliminary data on the efficacy of CBD for cannabis use disorders show mixed findings.
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The high rates and earlier onset of cannabis use, the legalization of “medical” marijuana (cannabis) and recreational cannabis use in some states, the increasing availability and use of edible cannabinoid products and highly potent synthetic cannabinoids, and the increasing potency of cannabis warrant the need to understand the relationship between cannabinoids and psychosis.
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The results of this trial can potentially contribute with a new treatment paradigm for patients suffering from dual diagnosis by evaluating the efficacy of cannabidiol versus a first-choice second-generation antipsychotic (risperidone).
A systematic review of the effect of cannabidiol on cognitive function: Relevance to schizophrenia
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