Cannabidiol-Δ9-tetrahydrocannabinol interactions on acute pain and locomotor activity.

Abstract

BACKGROUND Previous studies suggest that cannabidiol (CBD) may potentiate or antagonize Δ9-tetrahydrocannabinol's (THC) effects. The current study examined sex differences in CBD modulation of THC-induced antinociception, hypolocomotion, and metabolism. METHODS In Experiment 1, CBD (0, 10 or 30mg/kg) was administered 15min before THC (0, 1.8, 3.2, 5.6 or… (More)
DOI: 10.1016/j.drugalcdep.2017.01.046

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