Canine taste nerve responses to monosodium glutamate and disodium guanylate: differentiation between umami and salt components with amiloride.

@article{Nakamura1991CanineTN,
  title={Canine taste nerve responses to monosodium glutamate and disodium guanylate: differentiation between umami and salt components with amiloride.},
  author={Masuhisa Nakamura and Kenzo Kurihara},
  journal={Brain research},
  year={1991},
  volume={541 1},
  pages={21-8}
}
It has been argued whether the 'umami substances' such as monosodium glutamate (MSG) and disodium 5'-guanylate (GMP) stimulate the salt receptor or the unique receptor to the umami substances. We examined effects of amiloride, which inhibited the canine chorda tympani nerve responses to salts such as NaCl, KCl and NH4Cl, in a competitive manner, on the nerve responses to the umami substances and differentiated between the umami and salt components. Amiloride shifted the dose-response curves for… CONTINUE READING

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