Canine neurotensin, neurotensin6–13 and neuromedin N: primary structures and receptor activity

@article{Mitra1990CanineNN,
  title={Canine neurotensin, neurotensin6–13 and neuromedin N: primary structures and receptor activity},
  author={S. P. Mitra and Koutarou Muraki and D. Brown and A. M. Parsons and R. Carraway},
  journal={Regulatory Peptides},
  year={1990},
  volume={28},
  pages={11-22}
}
  • S. P. Mitra, Koutarou Muraki, +2 authors R. Carraway
  • Published 1990
  • Biology, Medicine
  • Regulatory Peptides
  • Canine neurotensin (NT) and neuromedin N (NMN) were isolated from extracts of ileal mucosa using radioimmunoassay for detection. The structures determined were consistent with those predicted by earlier cDNA work. The molar ratio of NT to NMN was ca. 7, suggesting that the NT/NMN precursor, which contains one copy of each peptide, undergoes complex posttranslational processing or that other NT-precursors lacking NMN exist. In addition to NT, small quantities of NT6-13 and NT2-13 were obtained… CONTINUE READING
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