Canine malignant hyperthermia: diagnosis of susceptibility in a breeding colony.

@article{OBrien1983CanineMH,
  title={Canine malignant hyperthermia: diagnosis of susceptibility in a breeding colony.},
  author={Peter James O'Brien and P H Cribb and Ronald J. White and Ernest D. Olfert and Janet E. Steiss},
  journal={The Canadian veterinary journal = La revue veterinaire canadienne},
  year={1983},
  volume={24 6},
  pages={172-7}
}
Fifteen related dogs were studied for susceptibility to malignant hyperthermia using halothane challenge and caffeine contracture tests. These dogs had hypertrophied muscles, were of a nervous temperament and had rectal temperatures at the upper limit of the normal range. Clinical pathology findings were mild elevations of serum aspartate transaminase and mean corpuscular hemoglobin. In vitro caffeine contracture tests were performed on muscle biopsies from five of these dogs. The concentration… CONTINUE READING