Canine herpes-induced retinal dysplasia and associated ocular anomalies.

  title={Canine herpes-induced retinal dysplasia and associated ocular anomalies.},
  author={Daniel M. Albert and Meir Lahav and Leland Eugene Carmichael and Dean H. Percy},
  journal={Investigative ophthalmology},
  volume={15 4},
Thirty-eight newborn Beagle puppies from eight litters of a specific pathogen-free colony maintained in isolation were inoculated with canine herpesvirus. Pups were killed between one and 30 days after inoculation. Histopathologic studies were carried out on the eyes and other tissues in conjunction with fluorescent antibody and viral isolation studies. Evidence of ocular inflammation manifested by panuveitis with the presence of intranuclear inclusion bodies was usually seen by the fourth day… CONTINUE READING
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