Canine dilated cardiomyopathy: lymphocyte and cardiac alpha(1)- and beta-adrenoceptor concentrations in normal and affected great danes.

@article{Re1999CanineDC,
  title={Canine dilated cardiomyopathy: lymphocyte and cardiac alpha(1)- and beta-adrenoceptor concentrations in normal and affected great danes.},
  author={Giovanni Re and Luciana Bergamasco and Paola Badino and Michele Borgarelli and Rosangela Odore and Alberto Tarducci and Rosana Zanatta and Carlo Girardi},
  journal={Veterinary journal},
  year={1999},
  volume={158 2},
  pages={120-7}
}
Serum catecholamine levels and myocardial and lymphocyte adrenergic receptor (AR) concentrations were measured in adult great danes affected by canine dilated cardiomyopathy (DCM) and compared to those of healthy animals. A non-homogeneous population of beta -AR, consisting of beta(1)-AR and beta(2)-AR, was observed in healthy (41 and 59%, respectively) and affected (17 and 83%, respectively) dog lymphocytes. Binding assays revealed that total beta -AR, beta(1)-AR and alpha(1)-AR were… CONTINUE READING