Canine and Feline Models of Human Genetic Diseases and Their Contributions to Advancing Clinical Therapies


@inproceedings{Gurda2017CanineAF,
  title={Canine and Feline Models of Human Genetic Diseases and Their Contributions to Advancing Clinical Therapies
},
  author={Brittney L. Gurda and Allison M. Bradbury and Charles Herman Vite},
  booktitle={The Yale journal of biology and medicine},
  year={2017}
}
For many lethal or debilitating genetic disorders in patients there are no satisfactory therapies. Several barriers exist that hinder the developments of effective therapies including the limited availability of clinically relevant animal models that faithfully recapitulate human genetic disease. In 1974, the Referral Center for Animal Models of Human Genetic Disease (RCAM) was established by Dr. Donald F. Patterson and continued by Dr. Mark E. Haskins at the University of Pennsylvania with the… CONTINUE READING

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References

Publications referenced by this paper.
SHOWING 1-10 OF 98 REFERENCES

Identification of NiemannPick C 1 disease biomarkers through sphingolipid profiling

M Fan, R Sidhu, H Fujiwara
  • J Pharmacol Exp Ther
  • 2016

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