Canine X-linked muscular dystrophy: morphologic lesions.

  title={Canine X-linked muscular dystrophy: morphologic lesions.},
  author={Beth A. Valentine and Barry J. Cooper and John F. Cummings and Alexander de Lahunta},
  journal={Journal of the neurological sciences},
  volume={97 1},
Gross pathologic lesions and light microscopic and ultrastructural features of skeletal muscle lesions in canine X-linked muscular dystrophy (CXMD) were studied in dogs from 3 months to 6 years of age. Necrosis and regeneration were present at all ages, but were most prominent in the youngest dogs studied. Increased intracytoplasmic calcium, as evidenced by positive alizarin red S staining, was associated with fiber necrosis, but was also seen in small numbers of otherwise normal fibers… CONTINUE READING


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