Candiplanecin, a new antibiotic from Ampullariella regularis subsp. mannitophila subsp. nov. II. Isolation, physico-chemical characterization and biological activities.

Abstract

New antibiotic, candiplanecin, was found in the culture broth of an actinomycete identified as Ampullariella regularis subsp. mannitophila subsp. nov. Candiplanecin was produced by conventional submerged culture and isolated by column chromatography on Diaion HP 20 followed by extraction with ethyl acetate and further column chromatography on Sephadex LH-20 column and finally on PrepPAK-500/C18 column. The antimicrobial spectrum of the antibiotic revealed its activity against yeasts and fungi.

Cite this paper

@article{Itoh1981CandiplanecinAN, title={Candiplanecin, a new antibiotic from Ampullariella regularis subsp. mannitophila subsp. nov. II. Isolation, physico-chemical characterization and biological activities.}, author={Yoshito Itoh and A Torikata and Chikako Katayama and Tsuyoshi Haneishi and Makoto Arai}, journal={The Journal of antibiotics}, year={1981}, volume={34 8}, pages={934-7} }