Candidiasis drug discovery and development: new approaches targeting virulence for discovering and identifying new drugs.

@article{Pierce2013CandidiasisDD,
  title={Candidiasis drug discovery and development: new approaches targeting virulence for discovering and identifying new drugs.},
  author={Christopher G. Pierce and Jos{\'e} Luis L{\'o}pez-Ribot},
  journal={Expert opinion on drug discovery},
  year={2013},
  volume={8 9},
  pages={1117-26}
}
INTRODUCTION Targeting pathogenetic mechanisms, rather than essential processes, represents a very attractive alternative for the development of new antibiotics. This may be particularly important in the case of antimycotics, due to the urgent need for novel antifungal drugs and the paucity of selective fungal targets. The opportunistic pathogenic fungus Candida albicans is the main etiological agent of candidiasis, the most common human fungal infection. These infections carry unacceptably… CONTINUE READING
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