Candidate genes of anxiety-related behavior in HAB/LAB rats and mice: focus on vasopressin and glyoxalase-I.

@article{Landgraf2007CandidateGO,
  title={Candidate genes of anxiety-related behavior in HAB/LAB rats and mice: focus on vasopressin and glyoxalase-I.},
  author={Rainer Landgraf and Melanie S. Kessler and Mirjam Bunck and Christopher A. Murgatroyd and Dietmar Spengler and Marina Zimbelmann and Markus Nussbaumer and Ludwig Czibere and Christoph Wilhelm Turck and Nicolas Singewald and Dan Rujescu and Elisabeth Frank},
  journal={Neuroscience and biobehavioral reviews},
  year={2007},
  volume={31 1},
  pages={89-102}
}
Two animal models of trait anxiety, HAB/LAB rats and mice, are described, representing inborn extremes in anxiety-related behavior. The comprehensive phenotypical characterization included basal behavioral features, stress-coping strategies and neuroendocrine responses upon stressor exposure with HAB animals being hyper-anxious, preferring passive coping, emitting more stressor-induced ultrasonic vocalization calls and showing typical peculiarities of the hypothalamic-pituitary-adrenocortical… CONTINUE READING