Candidate genes for the hypoxic tumor phenotype.

@article{Koong2000CandidateGF,
  title={Candidate genes for the hypoxic tumor phenotype.},
  author={Albert C. Koong and Nicholas C. Denko and Karen M. Hudson and Cornelia Schindler and Lillian Marie Swiersz and Cameron J. Koch and Sydney M Evans and Hani Ibrahim and Quang Trong Le and David James Terris and Amato J. Giaccia},
  journal={Cancer research},
  year={2000},
  volume={60 4},
  pages={883-7}
}
In this study, we have analyzed changes induced by hypoxia at the transcriptional level of genes that could be responsible for a more aggressive phenotype. Using a series of DNA array membranes, we identified a group of hypoxia-induced genes that included plasminogen activator inhibitor-1 (PAI-1), insulin-like growth factor-binding protein 3 (IGFBP-3), endothelin-2, low-density lipoprotein receptor-related protein (LRP), BCL2-interacting killer (BIK), migration-inhibitory factor (MIF), matrix… CONTINUE READING
139 Citations
46 References
Similar Papers

Citations

Publications citing this paper.
Showing 1-10 of 139 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 46 references

Similar Papers

Loading similar papers…