Candidate genes for temporal lobe epilepsy: a replication study

  title={Candidate genes for temporal lobe epilepsy: a replication study},
  author={Annick Salzmann and Nader Ali Perroud and Arielle Crespel and Carmen Lambercy and Alain Malafosse},
  journal={Neurological Sciences},
The objective of this study is to replicate previously published results regarding the involvement of several susceptibility genes in temporal lobe epilepsy (TLE): interleukin 1β (IL-1β), interleukin 1β (IL-1α), interleukin 1RA (IL-1RA), apolipoprotein E (ApoE) and prodynorphin (PDYN). We used a case-control approach comparing several polymorphisms within these candidate genes between unrelated TLE patients and matched controls. We were thus able to confirm the role of ApoE, IL-1α and IL-1RA… CONTINUE READING


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