Candidate gene association study for noise-induced hearing loss in two independent noise-exposed populations.

@article{Konings2009CandidateGA,
  title={Candidate gene association study for noise-induced hearing loss in two independent noise-exposed populations.},
  author={Annelies Konings and Lut Van Laer and Aneta Wiktorek-Smagur and Elżbieta Rajkowska and Malgorzata Pawelczyk and Per Carlsson and M L Bondeson and Adam Dudarewicz and Ann Vandevelde and Erik Fransen and Joke Huyghe and Eva Borg and Mariola Śliwińska-Kowalska and Guy Van Camp},
  journal={Annals of human genetics},
  year={2009},
  volume={73 2},
  pages={
          215-24
        }
}
Millions of people are daily exposed to high levels of noise. Consequently, noise-induced hearing loss (NIHL) is one of the most important occupational health hazards worldwide. In this study, we performed an association study for NIHL based on a candidate gene approach. 644 Single Nucleotide Polymorphisms (SNPs) in 53 candidate genes were analyzed in two independent NIHL sample sets, a Swedish set and part of a Polish set. Eight SNPs with promising results were selected and analysed in the… CONTINUE READING
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